Based on looking back at the treatment of the only surviving victims of Bacillus anthracis inhalation disease, the CDC is now recommending combination antibiotic therapy for any cases where there exists a high level of suspicion of the disease. As important, while every isolate of B. anthracis has been susceptible to penicillin, solo therapy with the drug is not recommended, because of the pressure it exerts toward development of antibiotic-resistant drugs. (As expected, the CDC’s anthrax web page is a great source of information.)